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Probiotics in Extreme Prematurity in Scandinavia
The PEPS Trial
Welcome to the PEPS trial!
A multicenter, double-blinded, registry-based randomized controlled trial
The Probiotics in Extreme Prematurity in Scandinavia (PEPS) Trial is an ongoing study in Sweden, Denmark, and Germany. The study enrolls extremely premature infants born before 28 weeks' gestational age and investigates whether probiotic supplementation reduces the risk of developing necrotizing enterocolitis (also called NEC) and neonatal mortality. Other important short- and long-term health outcomes will also be investigated over the duration of the study.
3
countries
12
university hospitals
27
satellite hospitals
170
babies included to date
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